For our backwards compatibility sins, we have plain POP3 exposed to the general Internet. This morning, we discovered that our POP3 server had more or less locked up around 6:30 am, apparently because someone decided to open up hundreds of connections to it and perform a brute force mass account/password attempt.
(In fact it took down our IMAP server too, because we're running Dovecot. This is one of the annoying limitations of Dovecot; there is a central server process that has a couple of file descriptors for every active connection. Run out of file descriptors here and everything grinds to a halt.)
In retrospect, this makes a great deal of sense for the attacker, because POP3 is a great protocol to go after. Not only do you get to try brute-forcing plaintext passwords, but you don't even have to spend any time and effort on handling an encryption protocol the way you do with mass ssh scanning; it's all in plain ASCII. Some testing suggests that you can even pipeline the commands.
(You still need many parallel connections, because Dovecot pauses for a while after a failed password even thought this doesn't do anything effective .)
I've found myself wondering if the attacker might have been a would be spammer wanting to mine people's email for highly useful live addresses instead of a cracker looking for logins, since there is no guarantee that a POP3 account will get you a real login.